PDB Information

PDB6BMW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Dual Allosteric Inhibition of SHP2 Phosphatase.
Fodor, M., Price, E., Wang, P., Lu, H., Argintaru, A., Chen, Z., Glick, M., Hao, H.X., Kato, M., Koenig, R., LaRochelle, J.R., Liu, G., McNeill, E., Majumdar, D., Nishiguchi, G.A., Perez, L.B., Paris, G., Quinn, C.M., Ramsey, T., Sendzik, M., Shultz, M.D., Williams, S.L., Stams, T., Blacklow, S.C., Acker, M.G., LaMarche, M.J.
ACS Chem. Biol.
HeaderHydrolase/Hydrolase Inhibitor
Released2017-11-15
Resolution2.100
CATH Insert Date03 Jun, 2018

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
6bmwA01 28 Jun, 2018 3.30.505.10 Assigned
6bmwA02 28 Jun, 2018 3.30.505.10 Assigned
6bmwA03 28 Jun, 2018 3.90.190.10 Assigned
6bmwB01 28 Jun, 2018 3.30.505.10 Assigned
6bmwB02 28 Jun, 2018 3.30.505.10 Assigned
6bmwB03 28 Jun, 2018 3.90.190.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q06124 PTN11_HUMAN Homo sapiens Tyrosine-protein phosphatase non-receptor type 11
Q06124 PTN11_HUMAN Homo sapiens Tyrosine-protein phosphatase non-receptor type 11
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