PDB 6bfq

PDB Information

PDB6BFQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities.
Dhagat, U., Hercus, T.R., Broughton, S.E., Nero, T.L., Cheung Tung Shing, K.S., Barry, E.F., Thomson, C.A., Bryson, S., Pai, E.F., McClure, B.J., Schrader, J.W., Lopez, A.F., Parker, M.W.
MAbs
HeaderImmune System
Released2017-10-26
Resolution2.600
CATH Insert Date16 Sep, 2018

PDB Images (33)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 16 Sep, 2018 Chopped
B 16 Sep, 2018 Chopped
C 16 Sep, 2018 Chopped
D 16 Sep, 2018 Chopped
E 16 Sep, 2018 Chopped
F 16 Sep, 2018 Chopped
G 16 Sep, 2018 Chopped
H 16 Sep, 2018 Chopped
I 16 Sep, 2018 Chopped
J 16 Sep, 2018 Chopped
K 16 Sep, 2018 Chopped
L 16 Sep, 2018 Chopped

CATH Domains (20)

Domain ID Date inserted into CATH Superfamily CATH Status
6bfqA01 17 Sep, 2018 Holding pen
6bfqA02 17 Sep, 2018 2.60.40.10 Assigned
6bfqB01 17 Sep, 2018 2.60.40.10 Assigned
6bfqB02 17 Sep, 2018 2.60.40.10 Assigned
6bfqC01 17 Sep, 2018 Holding pen
6bfqC02 17 Sep, 2018 2.60.40.10 Assigned
6bfqD01 17 Sep, 2018 2.60.40.10 Assigned
6bfqD02 17 Sep, 2018 2.60.40.10 Assigned
6bfqE01 17 Sep, 2018 Holding pen
6bfqE02 17 Sep, 2018 2.60.40.10 Assigned
6bfqF01 17 Sep, 2018 2.60.40.10 Assigned
6bfqF02 17 Sep, 2018 2.60.40.10 Assigned
6bfqG00 17 Sep, 2018 1.20.1250.10 Assigned
6bfqH01 17 Sep, 2018 Holding pen
6bfqH02 17 Sep, 2018 2.60.40.10 Assigned
6bfqI00 17 Sep, 2018 1.20.1250.10 Assigned
6bfqJ00 17 Sep, 2018 1.20.1250.10 Assigned
6bfqK00 17 Sep, 2018 1.20.1250.10 Assigned
6bfqL01 17 Sep, 2018 2.60.40.10 Assigned
6bfqL02 17 Sep, 2018 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04141 CSF2_HUMAN Homo sapiens Granulocyte-macrophage colony-stimulating factor
P04141 CSF2_HUMAN Homo sapiens Granulocyte-macrophage colony-stimulating factor
P04141 CSF2_HUMAN Homo sapiens Granulocyte-macrophage colony-stimulating factor
P04141 CSF2_HUMAN Homo sapiens Granulocyte-macrophage colony-stimulating factor