PDB 6b7h

PDB Information

PDB6B7H
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Synthesis and Pharmacological Characterization of C4beta-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu3Receptor Agonist.
Monn, J.A., Henry, S.S., Massey, S.M., Clawson, D.K., Chen, Q., Diseroad, B.A., Bhardwaj, R.M., Atwell, S., Lu, F., Wang, J., Russell, M., Heinz, B.A., Wang, X.S., Carter, J.H., Getman, B.G., Adragni, K., Broad, L.M., Sanger, H.E., Ursu, D., Catlow, J.T., Swanson, S., Johnson, B.G., Shaw, D.B., McKinzie, D.L., Hao, J.
J. Med. Chem.
HeaderMembrane Protein/Agonist
Released2017-10-04
Resolution2.820
CATH Insert Date03 Jun, 2018

PDB Images (2)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q14832 GRM3_HUMAN Homo sapiens Metabotropic glutamate receptor 3