PDB 6b4u

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Overview

PDB Information

PDB	6B4U
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity. Bruncko, M., Wang, L., Sheppard, G.S., Phillips, D.C., Tahir, S.K., Xue, J., Erickson, S., Fidanze, S., Fry, E., Hasvold, L., Jenkins, G.J., Jin, S., Judge, R.A., Kovar, P.J., Madar, D., Nimmer, P., Park, C., Petros, A.M., Rosenberg, S.H., Smith, M.L., Song, X., Sun, C., Tao, Z.F., Wang, X., Xiao, Y., Zhang, H., Tse, C., Leverson, J.D., Elmore, S.W., Souers, A.J. J. Med. Chem.
Header	Signaling Protein/Inhibitor
Released	2017-09-27
Resolution	1.950
CATH Insert Date	14 Nov, 2017

PDB Images (3)

Image of CATH 6b4u

6b4u

PDB 6b4u

Image of CATH 6b4uA

6b4uA

PDB Chain 6b4uA

Image of CATH 6b4uA01

6b4uA01

CATH Domain 6b4uA01

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6b4uA01	10 Dec, 2017	1.10.437.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1