PDB 6arv

PDB Information

PDB6ARV
MethodX-RAY DIFFRACTION
Host OrganismInsect cell expression vector pTIE1
Gene SourceHomo sapiens
Primary Citation
Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma.
Drew, A.E., Moradei, O., Jacques, S.L., Rioux, N., Boriack-Sjodin, A.P., Allain, C., Scott, M.P., Jin, L., Raimondi, A., Handler, J.L., Ott, H.M., Kruger, R.G., McCabe, M.T., Sneeringer, C., Riera, T., Shapiro, G., Waters, N.J., Mitchell, L.H., Duncan, K.W., Moyer, M.P., Copeland, R.A., Smith, J., Chesworth, R., Ribich, S.A.
Sci Rep
HeaderTransferase
Released2017-08-23
Resolution2.000
CATH Insert Date03 Jun, 2018

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped
D 03 Jun, 2018 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6arvA01 28 Jun, 2018 3.40.50.150 Assigned
6arvA02 28 Jun, 2018 2.70.160.11 Assigned
6arvB01 28 Jun, 2018 3.40.50.150 Assigned
6arvB02 28 Jun, 2018 2.70.160.11 Assigned
6arvC01 28 Jun, 2018 3.40.50.150 Assigned
6arvC02 28 Jun, 2018 2.70.160.11 Assigned
6arvD01 28 Jun, 2018 3.40.50.150 Assigned
6arvD02 28 Jun, 2018 2.70.160.11 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q86X55 CARM1_HUMAN Homo sapiens Histone-arginine methyltransferase CARM1
Q86X55 CARM1_HUMAN Homo sapiens Histone-arginine methyltransferase CARM1
Q86X55 CARM1_HUMAN Homo sapiens Histone-arginine methyltransferase CARM1
Q86X55 CARM1_HUMAN Homo sapiens Histone-arginine methyltransferase CARM1