×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

PDB Information

PDB6AFR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli K-12
Gene SourceHomo sapiens
Primary Citation
Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors
Xing, J., Zhang, R., Jiang, X., Hu, T., Wang, X., Qiao, G., Wang, J., Yang, F., Luo, X., Chen, K., Shen, J., Luo, C., Jiang, H., Zheng, M.
Eur J Med Chem
HeaderSignaling Protein/Inhibitor
Released2018-08-08
Resolution2.000
CATH Insert Date16 Dec, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
6afrA01 28 Feb, 2019 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
CATH-Gene3D is a Global Biodata Core Resource Learn more...