PDB 6aaj

PDB Links
Overview

PDB Information

PDB	6AAJ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor Hamaguchi, H., Amano, Y., Moritomo, A., Shirakami, S., Nakajima, Y., Nakai, K., Nomura, N., Ito, M., Higashi, Y., Inoue, T. Bioorg. Med. Chem.
Header	Transferase/Inhibitor
Released	2018-07-18
Resolution	2.370
CATH Insert Date	19 Aug, 2018

PDB Images (7)

Image of CATH 6aaj

6aaj

PDB 6aaj

Image of CATH 6aajA

6aajA

PDB Chain 6aajA

Image of CATH 6aajB

6aajB

PDB Chain 6aajB

Image of CATH 6aajA01

6aajA01

CATH Domain 6aajA01

Image of CATH 6aajA02

6aajA02

CATH Domain 6aajA02

Image of CATH 6aajB01

6aajB01

CATH Domain 6aajB01

Image of CATH 6aajB02

6aajB02

CATH Domain 6aajB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	19 Aug, 2018	Chopped
B	19 Aug, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6aajA01	20 Aug, 2018	3.30.200.20	Assigned
6aajA02	20 Aug, 2018	1.10.510.10	Assigned
6aajB01	20 Aug, 2018	3.30.200.20	Assigned
6aajB02	20 Aug, 2018	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2