PDB 5zya

PDB Information

PDB5ZYA
MethodELECTRON MICROSCOPY
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action
Finci, L.I., Zhang, X., Huang, X., Zhou, Q., Tsai, J., Teng, T., Agrawal, A., Chan, B., Irwin, S., Karr, C., Cook, A., Zhu, P., Reynolds, D., Smith, P.G., Fekkes, P., Buonamici, S., Larsen, N.A.
Genes Dev.
HeaderSplicing
Released2018-05-23
Resolution3.950
CATH Insert Date06 Jul, 2018

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Holding pen
B 06 Jul, 2018 Chopped
C 06 Jul, 2018 Holding pen
D 06 Jul, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5zyaB00 19 Jul, 2018 Holding pen
5zyaD00 19 Jul, 2018 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q15393 SF3B3_HUMAN Homo sapiens Splicing factor 3B subunit 3
O75533 SF3B1_HUMAN Homo sapiens Splicing factor 3B subunit 1