PDB Information

PDB5XV7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli K-12
Gene SourceHomo sapiens
Primary Citation
SRPKIN-1: A Covalent SRPK1/2 Inhibitor that Potently Converts VEGF from Pro-angiogenic to Anti-angiogenic Isoform
Hatcher, J.M., Wu, G., Zeng, C., Zhu, J., Meng, F., Patel, S., Wang, W., Ficarro, S.B., Leggett, A.L., Powell, C.E., Marto, J.A., Zhang, K., Ki Ngo, J.C., Fu, X.D., Zhang, T., Gray, N.S.
Cell Chem Biol
HeaderTransferase/Inhibitor
Released2017-06-26
Resolution2.320
CATH Insert Date03 Jun, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5xv7A01 28 Jun, 2018 3.30.200.20 Assigned
5xv7A02 28 Jun, 2018 Holding pen

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q96SB4 SRPK1_HUMAN Homo sapiens SRSF protein kinase 1