PDB Information

PDB5XMP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourcePlasmodium vivax
Primary Citation
Conformational Aspects in the Design of Inhibitors for Serine Hydroxymethyltransferase (SHMT): Biphenyl, Aryl Sulfonamide, and Aryl Sulfone Motifs
Schwertz, G., Frei, M.S., Witschel, M.C., Rottmann, M., Leartsakulpanich, U., Chitnumsub, P., Jaruwat, A., Ittarat, W., Schafer, A., Aponte, R.A., Trapp, N., Mark, K., Chaiyen, P., Diederich, F.
Chemistry
HeaderTransferase/Transferase Inhibitor
Released2017-05-16
Resolution2.400
CATH Insert Date17 Dec, 2017

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 17 Dec, 2017 Chopped
B 17 Dec, 2017 Chopped
C 17 Dec, 2017 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5xmpA01 23 Dec, 2017 3.90.1150.10 Assigned
5xmpA02 23 Dec, 2017 3.40.640.10 Assigned
5xmpB01 23 Dec, 2017 3.90.1150.10 Assigned
5xmpB02 23 Dec, 2017 3.40.640.10 Assigned
5xmpC01 23 Dec, 2017 3.90.1150.10 Assigned
5xmpC02 23 Dec, 2017 3.40.640.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
A5K8L9 A5K8L9_PLAVS Plasmodium vivax Sal-1 Serine hydroxymethyltransferase, putative
A5K8L9 A5K8L9_PLAVS Plasmodium vivax Sal-1 Serine hydroxymethyltransferase, putative
A5K8L9 A5K8L9_PLAVS Plasmodium vivax Sal-1 Serine hydroxymethyltransferase, putative