PDB Information

PDB5XFJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
LY2874455 potently inhibits FGFR gatekeeper mutants and overcomes mutation-based resistance.
Wu, D., Guo, M., Min, X., Dai, S., Li, M., Tan, S., Li, G., Chen, X., Ma, Y., Li, J., Jiang, L., Qu, L., Zhou, Z., Chen, Z., Chen, L., Xu, G., Chen, Y.
Chem. Commun. (Camb.)
HeaderTransferase
Released2017-04-10
Resolution3.250
CATH Insert Date12 Aug, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 12 Aug, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5xfjA01 13 Aug, 2018 3.30.200.20 Assigned
5xfjA02 13 Aug, 2018 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P22455 FGFR4_HUMAN Homo sapiens Fibroblast growth factor receptor 4