PDB 5x66
PDB Information
| PDB | 5X66 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem.
|
| Header | Transferase |
| Released | 2017-02-21 |
| Resolution | 1.990 |
| CATH Insert Date | 14 Nov, 2017 |
PDB Images (13)
5x66
PDB 5x66
5x66A
PDB Chain 5x66A
5x66B
PDB Chain 5x66B
5x66C
PDB Chain 5x66C
5x66D
PDB Chain 5x66D
5x66E
PDB Chain 5x66E
5x66F
PDB Chain 5x66F
5x66A00
CATH Domain 5x66A00
5x66B00
CATH Domain 5x66B00
5x66C00
CATH Domain 5x66C00
5x66D00
CATH Domain 5x66D00
5x66E00
CATH Domain 5x66E00
5x66F00
CATH Domain 5x66F00
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 14 Nov, 2017 | Chopped |
| B | 14 Nov, 2017 | Chopped |
| C | 14 Nov, 2017 | Chopped |
| D | 14 Nov, 2017 | Chopped |
| E | 14 Nov, 2017 | Chopped |
| F | 14 Nov, 2017 | Chopped |
CATH Domains (6)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 5x66A00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x66B00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x66C00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x66D00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x66E00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x66F00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
UniProtKB Entries (6)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
