PDB Information

PDB5X5A
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
Chen, D., Jansson, A., Sim, D., Larsson, A., Nordlund, P.
J. Biol. Chem.
HeaderTransferase
Released2017-02-15
Resolution2.390
CATH Insert Date14 Nov, 2017

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped
E 14 Nov, 2017 Chopped
F 14 Nov, 2017 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5x5aA00 10 Dec, 2017 3.30.572.10 Assigned
5x5aB00 10 Dec, 2017 3.30.572.10 Assigned
5x5aC00 10 Dec, 2017 3.30.572.10 Assigned
5x5aD00 10 Dec, 2017 3.30.572.10 Assigned
5x5aE00 10 Dec, 2017 3.30.572.10 Assigned
5x5aF00 10 Dec, 2017 3.30.572.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
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