PDB Information

PDB5WUX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli-Pichia pastoris shuttle vector pPpB1GAP_S
Gene SourceHomo sapiens
Primary Citation
Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases
Lee, J.U., Shin, W., Son, J.Y., Yoo, K.Y., Heo, Y.S.
Int J Mol Sci
HeaderImmune System
Released2016-12-21
Resolution2.900
CATH Insert Date14 Nov, 2017

PDB Images (25)

PDB Prints

PDB Chains (9)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped
E 14 Nov, 2017 Chopped
F 14 Nov, 2017 Chopped
G 14 Nov, 2017 Chopped
H 14 Nov, 2017 Chopped
L 14 Nov, 2017 Chopped

CATH Domains (15)

Domain ID Date inserted into CATH Superfamily CATH Status
5wuxA01 10 Dec, 2017 Holding pen
5wuxA02 10 Dec, 2017 2.60.40.10 Assigned
5wuxB01 10 Dec, 2017 2.60.40.10 Assigned
5wuxB02 10 Dec, 2017 2.60.40.10 Assigned
5wuxC01 10 Dec, 2017 Holding pen
5wuxC02 10 Dec, 2017 2.60.40.10 Assigned
5wuxD01 10 Dec, 2017 2.60.40.10 Assigned
5wuxD02 10 Dec, 2017 2.60.40.10 Assigned
5wuxE00 10 Dec, 2017 2.60.120.40 Assigned
5wuxF00 10 Dec, 2017 2.60.120.40 Assigned
5wuxG00 10 Dec, 2017 2.60.120.40 Assigned
5wuxH01 10 Dec, 2017 Holding pen
5wuxH02 10 Dec, 2017 2.60.40.10 Assigned
5wuxL01 10 Dec, 2017 2.60.40.10 Assigned
5wuxL02 10 Dec, 2017 2.60.40.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P01375 TNFA_HUMAN Homo sapiens Tumor necrosis factor
P01375 TNFA_HUMAN Homo sapiens Tumor necrosis factor
P01375 TNFA_HUMAN Homo sapiens Tumor necrosis factor