PDB 5w85

PDB Links
Overview

PDB Information

PDB	5W85
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors. Bhide, R.S., Keon, A., Weigelt, C., Sack, J.S., Schmidt, R.J., Lin, S., Xiao, H.Y., Spergel, S.H., Kempson, J., Pitts, W.J., Carman, J., Poss, M.A. Bioorg. Med. Chem. Lett.
Header	Transferase/Transferase Inhibitor
Released	2017-06-21
Resolution	2.250
CATH Insert Date	14 Nov, 2017

PDB Images (7)

Image of CATH 5w85

5w85

PDB 5w85

Image of CATH 5w85A

5w85A

PDB Chain 5w85A

Image of CATH 5w85B

5w85B

PDB Chain 5w85B

Image of CATH 5w85A01

5w85A01

CATH Domain 5w85A01

Image of CATH 5w85A02

5w85A02

CATH Domain 5w85A02

Image of CATH 5w85B01

5w85B01

CATH Domain 5w85B01

Image of CATH 5w85B02

5w85B02

CATH Domain 5w85B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped
B	14 Nov, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5w85A01	12 Jul, 2018	3.30.200.20	Assigned
5w85A02	12 Jul, 2018	1.10.510.10	Assigned
5w85B01	12 Jul, 2018	3.30.200.20	Assigned
5w85B02	12 Jul, 2018	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9NWZ3	IRAK4_HUMAN	Homo sapiens	Interleukin-1 receptor-associated kinase 4
Q9NWZ3	IRAK4_HUMAN	Homo sapiens	Interleukin-1 receptor-associated kinase 4