PDB 5w84

PDB Links
Overview

PDB Information

PDB	5W84
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors. Bhide, R.S., Keon, A., Weigelt, C., Sack, J.S., Schmidt, R.J., Lin, S., Xiao, H.Y., Spergel, S.H., Kempson, J., Pitts, W.J., Carman, J., Poss, M.A. Bioorg. Med. Chem. Lett.
Header	Transferase/Transferase Inhibitor
Released	2017-06-21
Resolution	2.900
CATH Insert Date	14 Nov, 2017

PDB Images (7)

Image of CATH 5w84

5w84

PDB 5w84

Image of CATH 5w84A

5w84A

PDB Chain 5w84A

Image of CATH 5w84B

5w84B

PDB Chain 5w84B

Image of CATH 5w84A01

5w84A01

CATH Domain 5w84A01

Image of CATH 5w84A02

5w84A02

CATH Domain 5w84A02

Image of CATH 5w84B01

5w84B01

CATH Domain 5w84B01

Image of CATH 5w84B02

5w84B02

CATH Domain 5w84B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped
B	14 Nov, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5w84A01	12 Jul, 2018	3.30.200.20	Assigned
5w84A02	12 Jul, 2018	1.10.510.10	Assigned
5w84B01	12 Jul, 2018	3.30.200.20	Assigned
5w84B02	12 Jul, 2018	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9NWZ3	IRAK4_HUMAN	Homo sapiens	Interleukin-1 receptor-associated kinase 4
Q9NWZ3	IRAK4_HUMAN	Homo sapiens	Interleukin-1 receptor-associated kinase 4