PDB Information

PDB5W4V
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
6-Substituted quinolines as ROR gamma t inverse agonists.
Barbay, J.K., Cummings, M.D., Abad, M., Castro, G., Kreutter, K.D., Kummer, D.A., Maharoof, U., Milligan, C., Nishimura, R., Pierce, J., Schalk-Hihi, C., Spurlino, J., Tanis, V.M., Urbanski, M., Venkatesan, H., Wang, A., Woods, C., Wolin, R., Xue, X., Edwards, J.P., Fourie, A.M., Leonard, K.
Bioorg. Med. Chem. Lett.
HeaderNuclear Protein
Released2017-06-13
Resolution2.650
CATH Insert Date07 Jan, 2018

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 07 Jan, 2018 Chopped
B 07 Jan, 2018 Chopped
C 07 Jan, 2018 Chopped
D 07 Jan, 2018 Chopped
E 07 Jan, 2018 Chopped
F 07 Jan, 2018 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5w4vA00 11 Jan, 2018 1.10.565.10 Assigned
5w4vB00 11 Jan, 2018 1.10.565.10 Assigned
5w4vC00 11 Jan, 2018 1.10.565.10 Assigned
5w4vD00 11 Jan, 2018 1.10.565.10 Assigned
5w4vE00 11 Jan, 2018 1.10.565.10 Assigned
5w4vF00 11 Jan, 2018 1.10.565.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma