PDB 5vnd

PDB Information

PDB5VND
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma.
Joshi, J.J., Coffey, H., Corcoran, E., Tsai, J., Huang, C.L., Ichikawa, K., Prajapati, S., Hao, M.H., Bailey, S., Wu, J., Rimkunas, V., Karr, C., Subramanian, V., Kumar, P., MacKenzie, C., Hurley, R., Satoh, T., Yu, K., Park, E., Rioux, N., Kim, A., Lai, W.G., Yu, L., Zhu, P., Buonamici, S., Larsen, N., Fekkes, P., Wang, J., Warmuth, M., Reynolds, D.J., Smith, P.G., Selvaraj, A.
Cancer Res.
HeaderTransferase/Transferase Inhibitor
Released2017-04-30
Resolution2.200
CATH Insert Date14 Nov, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5vndA01 10 Dec, 2017 3.30.200.20 Assigned
5vndA02 10 Dec, 2017 1.10.510.10 Assigned
5vndB01 10 Dec, 2017 3.30.200.20 Assigned
5vndB02 10 Dec, 2017 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P11362 FGFR1_HUMAN Homo sapiens Fibroblast growth factor receptor 1
P11362 FGFR1_HUMAN Homo sapiens Fibroblast growth factor receptor 1