PDB Information

PDB5VL7
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists.
Zhang, Y., Ultsch, M., Skelton, N.J., Burdick, D.J., Beresini, M.H., Li, W., Kong-Beltran, M., Peterson, A., Quinn, J., Chiu, C., Wu, Y., Shia, S., Moran, P., Di Lello, P., Eigenbrot, C., Kirchhofer, D.
Nat. Struct. Mol. Biol.
HeaderHydrolase
Released2017-04-25
Resolution3.500
CATH Insert Date14 Nov, 2017

PDB Images (12)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
H 14 Nov, 2017 Chopped
L 14 Nov, 2017 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
5vl7A01 10 Dec, 2017 3.30.70.80 Assigned
5vl7B01 04 May, 2018 3.40.50.200 Assigned
5vl7B02 04 May, 2018 2.60.120.690 Assigned
5vl7H01 10 Dec, 2017 Holding pen
5vl7H02 10 Dec, 2017 2.60.40.10 Assigned
5vl7L01 10 Dec, 2017 2.60.40.10 Assigned
5vl7L02 10 Dec, 2017 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9