PDB 5vio

PDB Information

PDB5VIO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Rational approach to highly potent and selective apoptosis signal-regulating kinase 1 (ASK1) inhibitors.
Lovering, F., Morgan, P., Allais, C., Aulabaugh, A., Brodfuehrer, J., Chang, J., Coe, J., Ding, W., Dowty, H., Fleming, M., Frisbie, R., Guzova, J., Hepworth, D., Jasti, J., Kortum, S., Kurumbail, R., Mohan, S., Papaioannou, N., Strohbach, J.W., Vincent, F., Lee, K., Zapf, C.W.
Eur J Med Chem
HeaderTransferase/Transferase Inhibitor
Released2017-04-17
Resolution2.840
CATH Insert Date03 Jun, 2018

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped
D 03 Jun, 2018 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5vioA01 28 Jun, 2018 3.30.200.20 Assigned
5vioA02 28 Jun, 2018 1.10.510.10 Assigned
5vioB01 28 Jun, 2018 3.30.200.20 Assigned
5vioB02 28 Jun, 2018 1.10.510.10 Assigned
5vioC01 28 Jun, 2018 3.30.200.20 Assigned
5vioC02 28 Jun, 2018 1.10.510.10 Assigned
5vioD01 28 Jun, 2018 3.30.200.20 Assigned
5vioD02 28 Jun, 2018 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q99683 M3K5_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 5
Q99683 M3K5_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 5
Q99683 M3K5_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 5
Q99683 M3K5_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 5
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