PDB 5vfc

PDB Information

PDB5VFC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction.
Karatas, H., Li, Y., Liu, L., Ji, J., Lee, S., Chen, Y., Yang, J., Huang, L., Bernard, D., Xu, J., Townsend, E.C., Cao, F., Ran, X., Li, X., Wen, B., Sun, D., Stuckey, J.A., Lei, M., Dou, Y., Wang, S.
J. Med. Chem.
HeaderTranscription/Inhibitor
Released2017-04-07
Resolution1.640
CATH Insert Date14 Nov, 2017

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5vfcA00 10 Dec, 2017 2.130.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
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