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PDB 5v9u

PDB Information

PDB5V9U
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor.
Janes, M.R., Zhang, J., Li, L.S., Hansen, R., Peters, U., Guo, X., Chen, Y., Babbar, A., Firdaus, S.J., Darjania, L., Feng, J., Chen, J.H., Li, S., Li, S., Long, Y.O., Thach, C., Liu, Y., Zarieh, A., Ely, T., Kucharski, J.M., Kessler, L.V., Wu, T., Yu, K., Wang, Y., Yao, Y., Deng, X., Zarrinkar, P.P., Brehmer, D., Dhanak, D., Lorenzi, M.V., Hu-Lowe, D., Patricelli, M.P., Ren, P., Liu, Y.
Cell
HeaderHydrolase/Hydrolase Inhibitor
Released2017-03-23
Resolution1.380
CATH Insert Date03 Jun, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5v9uA00 28 Jun, 2018 3.40.50.300 Assigned
5v9uB00 28 Jun, 2018 3.40.50.300 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P01116 RASK_HUMAN Homo sapiens GTPase KRas
P01116 RASK_HUMAN Homo sapiens GTPase KRas
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