PDB Information

PDB5V9O
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli K-12
Gene SourceHomo sapiens
Primary Citation
Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C.
Zeng, M., Lu, J., Li, L., Feru, F., Quan, C., Gero, T.W., Ficarro, S.B., Xiong, Y., Ambrogio, C., Paranal, R.M., Catalano, M., Shao, J., Wong, K.K., Marto, J.A., Fischer, E.S., Janne, P.A., Scott, D.A., Westover, K.D., Gray, N.S.
Cell Chem Biol
HeaderHydrolase/Hydrolase Inhibitor
Released2017-03-23
Resolution1.560
CATH Insert Date14 Nov, 2017

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5v9oA00 10 Dec, 2017 3.40.50.300 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P01116 RASK_HUMAN Homo sapiens GTPase KRas
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