PDB 5v84

PDB Information

PDB5V84
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2).
Crawford, T.D., Audia, J.E., Bellon, S., Burdick, D.J., Bommi-Reddy, A., Cote, A., Cummings, R.T., Duplessis, M., Flynn, E.M., Hewitt, M., Huang, H.R., Jayaram, H., Jiang, Y., Joshi, S., Kiefer, J.R., Murray, J., Nasveschuk, C.G., Neiss, A., Pardo, E., Romero, F.A., Sandy, P., Sims, R.J., Tang, Y., Taylor, A.M., Tsui, V., Wang, J., Wang, S., Wang, Y., Xu, Z., Zawadzke, L., Zhu, X., Albrecht, B.K., Magnuson, S.R., Cochran, A.G.
ACS Med Chem Lett
HeaderTranscription/Inhibitor
Released2017-03-21
Resolution2.700
CATH Insert Date14 Nov, 2017

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5v84A00 10 Dec, 2017 1.20.920.10 Assigned
5v84B00 10 Dec, 2017 1.20.920.10 Assigned
5v84C00 10 Dec, 2017 1.20.920.10 Assigned
5v84D00 10 Dec, 2017 1.20.920.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9BXF3 CECR2_HUMAN Homo sapiens Cat eye syndrome critical region protein 2
Q9BXF3 CECR2_HUMAN Homo sapiens Cat eye syndrome critical region protein 2
Q9BXF3 CECR2_HUMAN Homo sapiens Cat eye syndrome critical region protein 2
Q9BXF3 CECR2_HUMAN Homo sapiens Cat eye syndrome critical region protein 2