PDB Information

PDB5V19
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based drug design of novel ASK1 inhibitors using an integrated lead optimization strategy.
Gibson, T.S., Johnson, B., Fanjul, A., Halkowycz, P., Dougan, D.R., Cole, D., Swann, S.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Transferase Inhibitor
Released2017-03-01
Resolution3.100
CATH Insert Date07 May, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5v19A01 26 May, 2017 3.30.200.20 Assigned
5v19A02 26 May, 2017 1.10.510.10 Assigned
5v19B01 26 May, 2017 3.30.200.20 Assigned
5v19B02 26 May, 2017 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q99683 M3K5_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 5
Q99683 M3K5_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 5