PDB 5v0n

PDB Links
Overview

PDB Information

PDB	5V0N
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Design, synthesis, and X-ray structural studies of BACE-1 inhibitors containing substituted 2-oxopiperazines as P1'-P2' ligands. Ghosh, A.K., Brindisi, M., Yen, Y.C., Cardenas, E.L., Ella-Menye, J.R., Kumaragurubaran, N., Huang, X., Tang, J., Mesecar, A.D. Bioorg. Med. Chem. Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2017-02-28
Resolution	2.160
CATH Insert Date	14 May, 2017

PDB Images (10)

Image of CATH 5v0n

5v0n

PDB 5v0n

Image of CATH 5v0nA

5v0nA

PDB Chain 5v0nA

Image of CATH 5v0nB

5v0nB

PDB Chain 5v0nB

Image of CATH 5v0nC

5v0nC

PDB Chain 5v0nC

Image of CATH 5v0nA01

5v0nA01

CATH Domain 5v0nA01

Image of CATH 5v0nA02

5v0nA02

CATH Domain 5v0nA02

Image of CATH 5v0nB01

5v0nB01

CATH Domain 5v0nB01

Image of CATH 5v0nB02

5v0nB02

CATH Domain 5v0nB02

Image of CATH 5v0nC01

5v0nC01

CATH Domain 5v0nC01

Image of CATH 5v0nC02

5v0nC02

CATH Domain 5v0nC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	15 May, 2017	Chopped
B	15 May, 2017	Chopped
C	15 May, 2017	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5v0nA01	06 Nov, 2017	2.40.70.10	Assigned
5v0nA02	06 Nov, 2017	2.40.70.10	Assigned
5v0nB01	06 Nov, 2017	2.40.70.10	Assigned
5v0nB02	06 Nov, 2017	2.40.70.10	Assigned
5v0nC01	06 Nov, 2017	2.40.70.10	Assigned
5v0nC02	06 Nov, 2017	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1