PDB 5uoo
PDB Information
PDB | 5UOO |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor.
J. Med. Chem.
|
Header | Transcription |
Released | 2017-02-01 |
Resolution | 1.690 |
CATH Insert Date | 21 May, 2017 |
PDB Images (3)
PDB Prints
PDB Chains (1)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 22 May, 2017 | Chopped |
CATH Domains (1)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
5uooA00 | 06 Nov, 2017 | 1.20.920.10 | Assigned |
UniProtKB Entries (1)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
O60885 | BRD4_HUMAN | Homo sapiens | Bromodomain-containing protein 4 |