PDB 5ubr

PDB Information

PDB5UBR
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Discovery of 7-(3-(piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent and selective PI3K delta inhibitors.
Qin, L.Y., Ruan, Z., Cherney, R.J., Dhar, T.G., Neels, J., Weigelt, C.A., Sack, J.S., Srivastava, A.S., Cornelius, L.A., Tino, J.A., Stefanski, K., Gu, X., Xie, J., Susulic, V., Yang, X., Yarde-Chinn, M., Skala, S., Bosnius, R., Goldstein, C., Davies, P., Ruepp, S., Salter-Cid, L., Bhide, R.S., Poss, M.A.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Transferase Regulator
Released2016-12-21
Resolution2.400
CATH Insert Date07 May, 2017

PDB Images (2)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P42336 PK3CA_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform