PDB 5u7q

PDB Information

PDB5U7Q
MethodX-RAY DIFFRACTION
Host OrganismBaculovirus expression vector pFastBac1-HM
Gene SourceHomo sapiens
Primary Citation
Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones.
Kurasawa, O., Oguro, Y., Miyazaki, T., Homma, M., Mori, K., Iwai, K., Hara, H., Skene, R., Hoffman, I., Ohashi, A., Yoshida, S., Ishikawa, T., Cho, N.
Bioorg. Med. Chem.
HeaderTransferase
Released2016-12-12
Resolution3.150
CATH Insert Date07 May, 2017

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Chopped
D 08 May, 2017 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5u7qA01 07 Mar, 2018 3.30.200.20 Assigned
5u7qA02 07 Mar, 2018 1.10.510.10 Assigned
5u7qB01 07 Mar, 2018 3.30.200.20 Assigned
5u7qB02 07 Mar, 2018 1.10.510.10 Assigned
5u7qC01 07 Mar, 2018 3.30.200.20 Assigned
5u7qC02 07 Mar, 2018 1.10.510.10 Assigned
5u7qD01 07 Mar, 2018 3.30.200.20 Assigned
5u7qD02 07 Mar, 2018 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2