PDB 5tyi

PDB Information

PDB5TYI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.
Watson, G.M., Kulkarni, K., Sang, J., Ma, X., Gunzburg, M.J., Perlmutter, P., Wilce, M.C.J., Wilce, J.A.
J. Med. Chem.
HeaderSignaling Protein/Peptide
Released2016-11-20
Resolution2.150
CATH Insert Date17 Dec, 2017

PDB Images (13)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 17 Dec, 2017 Chopped
B 17 Dec, 2017 Chopped
C 17 Dec, 2017 Chopped
D 17 Dec, 2017 Chopped
L 17 Dec, 2017 Rejected
M 17 Dec, 2017 Rejected
N 17 Dec, 2017 Rejected
P 17 Dec, 2017 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5tyiA00 22 Dec, 2017 3.30.505.10 Assigned
5tyiB00 22 Dec, 2017 3.30.505.10 Assigned
5tyiC00 22 Dec, 2017 3.30.505.10 Assigned
5tyiD00 22 Dec, 2017 3.30.505.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7