PDB Information

PDB5TX6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
Kim, S.K., Barron, L., Hinck, C.S., Petrunak, E.M., Cano, K.E., Thangirala, A., Iskra, B., Brothers, M., Vonberg, M., Leal, B., Richter, B., Kodali, R., Taylor, A.B., Du, S., Barnes, C.O., Sulea, T., Calero, G., Hart, P.J., Hart, M.J., Demeler, B., Hinck, A.P.
J. Biol. Chem.
HeaderCytokine
Released2016-11-15
Resolution2.750
CATH Insert Date07 May, 2017

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
5tx6A00 22 May, 2017 2.10.90.10 Assigned
5tx6B00 22 May, 2017 2.10.90.10 Assigned
5tx6C00 22 May, 2017 2.10.90.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P27090 TGFB2_MOUSE Mus musculus Transforming growth factor beta-2 proprotein
P27090 TGFB2_MOUSE Mus musculus Transforming growth factor beta-2 proprotein
P27090 TGFB2_MOUSE Mus musculus Transforming growth factor beta-2 proprotein