PDB 5tq7

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Overview

PDB Information

PDB	5TQ7
Method	X-RAY DIFFRACTION
Host Organism	Homo sapiens
Gene Source	Homo sapiens
Primary Citation	Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin. Jones, P., Storer, R.I., Sabnis, Y.A., Wakenhut, F.M., Whitlock, G.A., England, K.S., Mukaiyama, T., Dehnhardt, C.M., Coe, J.W., Kortum, S.W., Chrencik, J.E., Brown, D.G., Jones, R.M., Murphy, J.R., Yeoh, T., Morgan, P., Kilty, I. J. Med. Chem.
Header	Transferase/Transferase Inhibitor
Released	2016-10-23
Resolution	2.100
CATH Insert Date	07 May, 2017

PDB Images (7)

Image of CATH 5tq7

5tq7

PDB 5tq7

Image of CATH 5tq7A

5tq7A

PDB Chain 5tq7A

Image of CATH 5tq7B

5tq7B

PDB Chain 5tq7B

Image of CATH 5tq7A01

5tq7A01

CATH Domain 5tq7A01

Image of CATH 5tq7A02

5tq7A02

CATH Domain 5tq7A02

Image of CATH 5tq7B01

5tq7B01

CATH Domain 5tq7B01

Image of CATH 5tq7B02

5tq7B02

CATH Domain 5tq7B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5tq7A01	22 May, 2017	3.30.200.20	Assigned
5tq7A02	22 May, 2017	1.10.510.10	Assigned
5tq7B01	22 May, 2017	3.30.200.20	Assigned
5tq7B02	22 May, 2017	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2