PDB 5toz

PDB Information

PDB5TOZ
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition.
Telliez, J.B., Dowty, M.E., Wang, L., Jussif, J., Lin, T., Li, L., Moy, E., Balbo, P., Li, W., Zhao, Y., Crouse, K., Dickinson, C., Symanowicz, P., Hegen, M., Banker, M.E., Vincent, F., Unwalla, R., Liang, S., Gilbert, A.M., Brown, M.F., Hayward, M., Montgomery, J., Yang, X., Bauman, J., Trujillo, J.I., Casimiro-Garcia, A., Vajdos, F.F., Leung, L., Geoghegan, K.F., Quazi, A., Xuan, D., Jones, L., Hett, E., Wright, K., Clark, J.D., Thorarensen, A.
ACS Chem. Biol.
HeaderTransferase/Transferase Inhibitor
Released2016-10-19
Resolution1.980
CATH Insert Date20 Nov, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Nov, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5tozA01 25 Nov, 2016 3.30.200.20 Assigned
5tozA02 25 Nov, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3