PDB 5tfu

PDB Links
Overview

PDB Information

PDB	5TFU
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli DH5[alpha]
Gene Source	Homo sapiens
Primary Citation	Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality. Butler, C.R., Ogilvie, K., Martinez-Alsina, L., Barreiro, G., Beck, E.M., Nolan, C.E., Atchison, K., Benvenuti, E., Buzon, L., Doran, S., Gonzales, C., Helal, C.J., Hou, X., Hsu, M.H., Johnson, E.F., Lapham, K., Lanyon, L., Parris, K., O'Neill, B.T., Riddell, D., Robshaw, A., Vajdos, F., Brodney, M.A. J. Med. Chem.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2016-09-26
Resolution	2.750
CATH Insert Date	07 May, 2017

PDB Images (9)

Image of CATH 5tfu

5tfu

PDB 5tfu

Image of CATH 5tfuA

5tfuA

PDB Chain 5tfuA

Image of CATH 5tfuB

5tfuB

PDB Chain 5tfuB

Image of CATH 5tfuC

5tfuC

PDB Chain 5tfuC

Image of CATH 5tfuD

5tfuD

PDB Chain 5tfuD

Image of CATH 5tfuA00

5tfuA00

CATH Domain 5tfuA00

Image of CATH 5tfuB00

5tfuB00

CATH Domain 5tfuB00

Image of CATH 5tfuC00

5tfuC00

CATH Domain 5tfuC00

Image of CATH 5tfuD00

5tfuD00

CATH Domain 5tfuD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped
C	08 May, 2017	Chopped
D	08 May, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5tfuA00	21 May, 2017	1.10.630.10	Assigned
5tfuB00	21 May, 2017	1.10.630.10	Assigned
5tfuC00	21 May, 2017	1.10.630.10	Assigned
5tfuD00	21 May, 2017	1.10.630.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P10635	CP2D6_HUMAN	Homo sapiens	Cytochrome P450 2D6
P10635	CP2D6_HUMAN	Homo sapiens	Cytochrome P450 2D6
P10635	CP2D6_HUMAN	Homo sapiens	Cytochrome P450 2D6
P10635	CP2D6_HUMAN	Homo sapiens	Cytochrome P450 2D6