PDB 5tc4

PDB Information

PDB5TC4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor.
Gustafsson, R., Jemth, A.S., Gustafsson, N.M., Farnegardh, K., Loseva, O., Wiita, E., Bonagas, N., Dahllund, L., Llona-Minguez, S., Haggblad, M., Henriksson, M., Andersson, Y., Homan, E., Helleday, T., Stenmark, P.
Cancer Res.
HeaderOxidoreductase
Released2016-09-14
Resolution1.890
CATH Insert Date08 Jan, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 09 Jan, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5tc4A01 20 Jan, 2017 3.40.50.720 Assigned
5tc4A02 20 Jan, 2017 3.40.50.10860 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P13995 MTDC_HUMAN Homo sapiens Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial