PDB 5t8q

PDB Information

PDB5T8Q
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceMus musculus
Primary Citation
Structure-Based Design of Tricyclic NF-kappa B Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K).
Castanedo, G.M., Blaquiere, N., Beresini, M., Bravo, B., Brightbill, H., Chen, J., Cui, H.F., Eigenbrot, C., Everett, C., Feng, J., Godemann, R., Gogol, E., Hymowitz, S., Johnson, A., Kayagaki, N., Kohli, P.B., Knuppel, K., Kraemer, J., Kruger, S., Loke, P., McEwan, P., Montalbetti, C., Roberts, D.A., Smith, M., Steinbacher, S., Sujatha-Bhaskar, S., Takahashi, R., Wang, X., Wu, L.C., Zhang, Y., Staben, S.T.
J. Med. Chem.
HeaderTransferase
Released2016-09-08
Resolution2.630
CATH Insert Date07 May, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5t8qA01 21 May, 2017 3.30.200.20 Assigned
5t8qA02 21 May, 2017 1.10.510.10 Assigned
5t8qB01 21 May, 2017 3.30.200.20 Assigned
5t8qB02 21 May, 2017 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9WUL6 M3K14_MOUSE Mus musculus Mitogen-activated protein kinase kinase kinase 14
Q9WUL6 M3K14_MOUSE Mus musculus Mitogen-activated protein kinase kinase kinase 14