PDB 5sw8

PDB Links
Overview

PDB Information

PDB	5SW8
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design. Miller, M.S., Maheshwari, S., McRobb, F.M., Kinzler, K.W., Amzel, L.M., Vogelstein, B., Gabelli, S.B. Bioorg. Med. Chem.
Header	Transferase/Transferase Inhibitor
Released	2016-08-08
Resolution	3.300
CATH Insert Date	14 May, 2017

PDB Images (5)

Image of CATH 5sw8

5sw8

PDB 5sw8

Image of CATH 5sw8A

5sw8A

PDB Chain 5sw8A

Image of CATH 5sw8B

5sw8B

PDB Chain 5sw8B

Image of CATH 5sw8B01

5sw8B01

CATH Domain 5sw8B01

Image of CATH 5sw8B02

5sw8B02

CATH Domain 5sw8B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	15 May, 2017	Holding pen
B	15 May, 2017	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5sw8B01	14 Nov, 2017		Holding pen
5sw8B02	14 Nov, 2017	1.10.287.1490	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P42336	PK3CA_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
P27986	P85A_HUMAN	Homo sapiens	Phosphatidylinositol 3-kinase regulatory subunit alpha