PDB 5pzk

PDB Information

PDB5PZK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus genotype 1b (isolate Con1)
Primary Citation
Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies.
Yeung, K.S., Beno, B.R., Parcella, K., Bender, J.A., Grant-Young, K.A., Nickel, A., Gunaga, P., Anjanappa, P., Bora, R.O., Selvakumar, K., Rigat, K., Wang, Y.K., Liu, M., Lemm, J., Mosure, K., Sheriff, S., Wan, C., Witmer, M., Kish, K., Hanumegowda, U., Zhuo, X., Shu, Y.Z., Parker, D., Haskell, R., Ng, A., Gao, Q., Colston, E., Raybon, J., Grasela, D.M., Santone, K., Gao, M., Meanwell, N.A., Sinz, M., Soars, M.G., Knipe, J.O., Roberts, S.B., Kadow, J.F.
J. Med. Chem.
HeaderTransferase
Released2017-02-27
Resolution2.200
CATH Insert Date21 May, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 22 May, 2017 Chopped
B 22 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5pzkA01 06 Nov, 2017 Holding pen
5pzkA02 06 Nov, 2017 Holding pen
5pzkB01 06 Nov, 2017 Holding pen
5pzkB02 06 Nov, 2017 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9WMX2 POLG_HCVCO Hepatitis C virus (isolate Con1) Genome polyprotein
Q9WMX2 POLG_HCVCO Hepatitis C virus (isolate Con1) Genome polyprotein