PDB 5osk

PDB Information

PDB5OSK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure.
Dohle, W., Jourdan, F.L., Menchon, G., Prota, A.E., Foster, P.A., Mannion, P., Hamel, E., Thomas, M.P., Kasprzyk, P.G., Ferrandis, E., Steinmetz, M.O., Leese, M.P., Potter, B.V.L.
J. Med. Chem.
HeaderCell Cycle
Released2017-08-17
Resolution2.110
CATH Insert Date07 Jan, 2018

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 07 Jan, 2018 Chopped
B 07 Jan, 2018 Chopped
C 07 Jan, 2018 Chopped
D 07 Jan, 2018 Chopped
E 07 Jan, 2018 Chopped
F 07 Jan, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
5oskA01 11 Jan, 2018 3.40.50.1440 Assigned
5oskA02 11 Jan, 2018 3.30.1330.20 Assigned
5oskA03 11 Jan, 2018 1.10.287.600 Assigned
5oskB01 11 Jan, 2018 3.40.50.1440 Assigned
5oskB02 11 Jan, 2018 3.30.1330.20 Assigned
5oskB03 11 Jan, 2018 1.10.287.600 Assigned
5oskC01 11 Jan, 2018 3.40.50.1440 Assigned
5oskC02 11 Jan, 2018 3.30.1330.20 Assigned
5oskC03 11 Jan, 2018 1.10.287.600 Assigned
5oskD01 11 Jan, 2018 3.40.50.1440 Assigned
5oskD02 11 Jan, 2018 3.30.1330.20 Assigned
5oskD03 11 Jan, 2018 1.10.287.600 Assigned
5oskE01 11 Jan, 2018 6.10.280.30 Assigned
5oskF01 11 Jan, 2018 3.40.50.11480 Assigned
5oskF02 11 Jan, 2018 3.30.470.20 Assigned
5oskF03 11 Jan, 2018 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein