PDB 5oqw

PDB Information

PDB5OQW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNF alpha-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth.
Ward, G.A., Lewis, E.J., Ahn, J.S., Johnson, C.N., Lyons, J.F., Martins, V., Munck, J.M., Rich, S.J., Smyth, T., Thompson, N.T., Williams, P.A., Wilsher, N.E., Wallis, N.G., Chessari, G.
Mol. Cancer Ther.
HeaderApoptosis
Released2017-08-14
Resolution2.310
CATH Insert Date06 Jul, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Chopped
B 06 Jul, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5oqwA00 19 Jul, 2018 1.10.1170.10 Assigned
5oqwB00 19 Jul, 2018 1.10.1170.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP