PDB 5opu

PDB Information

PDB5OPU
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1).
Williamson, D.S., Smith, G.P., Acheson-Dossang, P., Bedford, S.T., Chell, V., Chen, I.J., Daechsel, J.C.A., Daniels, Z., David, L., Dokurno, P., Hentzer, M., Herzig, M.C., Hubbard, R.E., Moore, J.D., Murray, J.B., Newland, S., Ray, S.C., Shaw, T., Surgenor, A.E., Terry, L., Thirstrup, K., Wang, Y., Christensen, K.V.
J. Med. Chem.
HeaderTransferase
Released2017-08-10
Resolution1.550
CATH Insert Date14 Nov, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5opuA01 10 Dec, 2017 3.30.200.20 Assigned
5opuA02 10 Dec, 2017 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14757 CHK1_HUMAN Homo sapiens Serine/threonine-protein kinase Chk1