PDB Information

PDB5O3E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition.
Runcie, A.C., Zengerle, M., Chan, K.H., Testa, A., van Beurden, L., Baud, M.G.J., Epemolu, O., Ellis, L.C.J., Read, K.D., Coulthard, V., Brien, A., Ciulli, A.
Chem Sci
HeaderTranscription
Released2017-05-23
Resolution1.400
CATH Insert Date03 Jun, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5o3eA00 27 Jun, 2018 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2