PDB 5nxe

PDB Information

PDB5NXE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors.
Nkizinkiko, Y., Desantis, J., Koivunen, J., Haikarainen, T., Murthy, S., Sancineto, L., Massari, S., Ianni, F., Obaji, E., Loza, M.I., Pihlajaniemi, T., Brea, J., Tabarrini, O., Lehtio, L.
Sci Rep
HeaderTransferase
Released2017-05-10
Resolution1.600
CATH Insert Date03 Jun, 2018

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
H 03 Jun, 2018 Chopped
I 03 Jun, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5nxeA00 27 Jun, 2018 3.90.228.10 Assigned
5nxeB00 27 Jun, 2018 3.90.228.10 Assigned
5nxeH00 27 Jun, 2018 6.20.320.10 Assigned
5nxeI00 27 Jun, 2018 6.20.320.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2