PDB Information

PDB5NSP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach.
Anumala, U.R., Waaler, J., Nkizinkiko, Y., Ignatev, A., Lazarow, K., Lindemann, P., Olsen, P.A., Murthy, S., Obaji, E., Majouga, A.G., Leonov, S., von Kries, J.P., Lehtio, L., Krauss, S., Nazare, M.
J. Med. Chem.
HeaderTransferase
Released2017-04-26
Resolution2.300
CATH Insert Date17 Dec, 2017

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Dec, 2017 Chopped
B 17 Dec, 2017 Chopped
C 17 Dec, 2017 Chopped
D 17 Dec, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5nspA00 22 Dec, 2017 3.90.228.10 Assigned
5nspB00 22 Dec, 2017 3.90.228.10 Assigned
5nspC00 22 Dec, 2017 6.20.320.10 Assigned
5nspD00 22 Dec, 2017 6.20.320.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2