PDB 5n8c

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Overview

PDB Information

PDB	5N8C
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Pseudomonas aeruginosa
Primary Citation	Structure-based discovery of LpxC inhibitors. Zhang, J., Chan, A., Lippa, B., Cross, J.B., Liu, C., Yin, N., Romero, J.A., Lawrence, J., Heney, R., Herradura, P., Goss, J., Clark, C., Abel, C., Zhang, Y., Poutsiaka, K.M., Epie, F., Conrad, M., Mahamoon, A., Nguyen, K., Chavan, A., Clark, E., Li, T.C., Cheng, R.K., Wood, M., Andersen, O.A., Brooks, M., Kwong, J., Barker, J., Parr, I.B., Gu, Y., Ryan, M.D., Coleman, S., Metcalf, C.A. Bioorg. Med. Chem. Lett.
Header	Hydrolase
Released	2017-02-23
Resolution	1.900
CATH Insert Date	07 May, 2017

PDB Images (7)

Image of CATH 5n8c

5n8c

PDB 5n8c

Image of CATH 5n8cA

5n8cA

PDB Chain 5n8cA

Image of CATH 5n8cB

5n8cB

PDB Chain 5n8cB

Image of CATH 5n8cA01

5n8cA01

CATH Domain 5n8cA01

Image of CATH 5n8cA02

5n8cA02

CATH Domain 5n8cA02

Image of CATH 5n8cB01

5n8cB01

CATH Domain 5n8cB01

Image of CATH 5n8cB02

5n8cB02

CATH Domain 5n8cB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5n8cA01	18 May, 2017	3.30.230.20	Assigned
5n8cA02	18 May, 2017	3.30.1700.10	Assigned
5n8cB01	18 May, 2017	3.30.230.20	Assigned
5n8cB02	18 May, 2017	3.30.1700.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P47205	LPXC_PSEAE	Pseudomonas aeruginosa PAO1	UDP-3-O-acyl-N-acetylglucosamine deacetylase
P47205	LPXC_PSEAE	Pseudomonas aeruginosa PAO1	UDP-3-O-acyl-N-acetylglucosamine deacetylase