PDB Information

PDB5N53
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer.
Unterlass, J.E., Basle, A., Blackburn, T.J., Tucker, J., Cano, C., Noble, M.E.M., Curtin, N.J.
Oncotarget
HeaderOxidoreductase
Released2017-02-12
Resolution1.480
CATH Insert Date07 May, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5n53A00 14 Dec, 2017 3.40.50.720 Assigned
5n53B00 14 Dec, 2017 3.40.50.720 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O43175 SERA_HUMAN Homo sapiens D-3-phosphoglycerate dehydrogenase
O43175 SERA_HUMAN Homo sapiens D-3-phosphoglycerate dehydrogenase