PDB Information

PDB5MYV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.
Batson, J., Toop, H.D., Redondo, C., Babaei-Jadidi, R., Chaikuad, A., Wearmouth, S.F., Gibbons, B., Allen, C., Tallant, C., Zhang, J., Du, C., Hancox, J.C., Hawtrey, T., Da Rocha, J., Griffith, R., Knapp, S., Bates, D.O., Morris, J.C.
ACS Chem. Biol.
HeaderTransferase
Released2017-01-29
Resolution2.900
CATH Insert Date14 May, 2017

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 15 May, 2017 Chopped
B 15 May, 2017 Chopped
C 15 May, 2017 Chopped
D 15 May, 2017 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5myvA01 06 Nov, 2017 3.30.200.20 Assigned
5myvA02 06 Nov, 2017 1.10.510.10 Assigned
5myvB01 06 Nov, 2017 3.30.200.20 Assigned
5myvB02 06 Nov, 2017 1.10.510.10 Assigned
5myvC01 06 Nov, 2017 3.30.200.20 Assigned
5myvC02 06 Nov, 2017 1.10.510.10 Assigned
5myvD01 06 Nov, 2017 3.30.200.20 Assigned
5myvD02 06 Nov, 2017 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P78362 SRPK2_HUMAN Homo sapiens SRSF protein kinase 2
P78362 SRPK2_HUMAN Homo sapiens SRSF protein kinase 2
P78362 SRPK2_HUMAN Homo sapiens SRSF protein kinase 2
P78362 SRPK2_HUMAN Homo sapiens SRSF protein kinase 2
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