PDB Information

PDB5MOW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066.
De Fusco, C., Brear, P., Iegre, J., Georgiou, K.H., Sore, H.F., Hyvonen, M., Spring, D.R.
Bioorg. Med. Chem.
HeaderTransferase
Released2016-12-14
Resolution1.860
CATH Insert Date14 Nov, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5mowA01 10 Dec, 2017 1.10.510.10 Assigned
5mowA02 10 Dec, 2017 3.30.200.20 Assigned
5mowB01 10 Dec, 2017 1.10.510.10 Assigned
5mowB02 10 Dec, 2017 3.30.200.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P68400 CSK21_HUMAN Homo sapiens Casein kinase II subunit alpha
P68400 CSK21_HUMAN Homo sapiens Casein kinase II subunit alpha