PDB Information

PDB5MN2
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Affimer proteins inhibit immune complex binding to Fc gamma RIIIa with high specificity through competitive and allosteric modes of action.
Robinson, J.I., Baxter, E.W., Owen, R.L., Thomsen, M., Tomlinson, D.C., Waterhouse, M.P., Win, S.J., Nettleship, J.E., Tiede, C., Foster, R.J., Owens, R.J., Fishwick, C.W.G., Harris, S.A., Goldman, A., McPherson, M.J., Morgan, A.W.
Proc. Natl. Acad. Sci. U.S.A.
HeaderImmune System
Released2016-12-12
Resolution2.350
CATH Insert Date07 Jan, 2018

PDB Images (11)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 07 Jan, 2018 Chopped
B 07 Jan, 2018 Chopped
C 07 Jan, 2018 Chopped
D 07 Jan, 2018 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5mn2A01 11 Jan, 2018 2.60.40.10 Assigned
5mn2A02 11 Jan, 2018 2.60.40.10 Assigned
5mn2B01 11 Jan, 2018 2.60.40.10 Assigned
5mn2B02 11 Jan, 2018 2.60.40.10 Assigned
5mn2C00 22 Feb, 2018 3.10.450.10 Assigned
5mn2D00 22 Feb, 2018 3.10.450.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P08637 FCG3A_HUMAN Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-A
P08637 FCG3A_HUMAN Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-A