PDB Information

PDB5MKV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia COLI
Gene SourceHomo sapiens
Primary Citation
Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Zheng, Y., Sethi, R., Mangala, L.S., Taylor, C., Goldsmith, J., Wang, M., Masuda, K., Karaminejadranjbar, M., Mannion, D., Miranda, F., Herrero-Gonzalez, S., Hellner, K., Chen, F., Alsaadi, A., Albukhari, A., Fotso, D.C., Yau, C., Jiang, D., Pradeep, S., Rodriguez-Aguayo, C., Lopez-Berestein, G., Knapp, S., Gray, N.S., Campo, L., Myers, K.A., Dhar, S., Ferguson, D., Bast, R.C., Sood, A.K., von Delft, F., Ahmed, A.A.
Nat Commun
HeaderHydrolase
Released2016-12-05
Resolution1.800
CATH Insert Date07 May, 2017

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Chopped
D 08 May, 2017 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5mkvA01 16 May, 2017 2.30.40.10 Assigned
5mkvA02 16 May, 2017 3.20.20.140 Assigned
5mkvB01 16 May, 2017 2.30.40.10 Assigned
5mkvB02 16 May, 2017 3.20.20.140 Assigned
5mkvC01 16 May, 2017 2.30.40.10 Assigned
5mkvC02 16 May, 2017 3.20.20.140 Assigned
5mkvD01 16 May, 2017 2.30.40.10 Assigned
5mkvD02 16 May, 2017 3.20.20.140 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q16555 DPYL2_HUMAN Homo sapiens Dihydropyrimidinase-related protein 2
Q16555 DPYL2_HUMAN Homo sapiens Dihydropyrimidinase-related protein 2
Q16555 DPYL2_HUMAN Homo sapiens Dihydropyrimidinase-related protein 2
Q16555 DPYL2_HUMAN Homo sapiens Dihydropyrimidinase-related protein 2